Host and Virus Face Off over RNA Modification

Host and Virus Face Off over RNA Modification

What happens when a mechanism meant to protect the cell gets exploited by bad-mannered viruses? 11.04.2019 Human cells infected with a CMV virus (green), in a control sample and in cells missing enzymes belonging to the m6A system (center and right) Viruses can be...
In Search of the First Enzymes

In Search of the First Enzymes

Proto-enzymes designed in the lab bound strongly to RNA and DNA, suggesting a surprising origin for these proteins 01.04.2019 Structural models derived from NMR data. (Upper) The observed major C-PLoop conformation. (Lower) Alignment of the β-(P-loop)-α elements of...